• Exercise training reduces alcohol consumption but does not affect HPA-axis activity in heavy drinkers 

      Georgakouli K., Manthou E., Georgoulias P., Ziaka A., Fatouros I.G., Mastorakos G., Koutedakis Y., Theodorakis Y., Jamurtas A.Z. (2017)
      Background It has been suggested that physical exercise could have potential beneficial effects in substance abusers, which are based on both physiological and psychological theories. Although a few studies have examined ...
    • HPA axis responses to acute exercise differ in smokers and non-smokers 

      Georgakouli K., Manthou E., Georgoulias P., Ziaka A., Deli C.K., Draganidis D., Batrakoulis A., Papanikolaou K., Tsimeas P., Mastorakos G., Fatouros I.G., Koutedakis Y., Theodorakis Y., Jamurtas A.Z. (2021)
      Physical exercise has been proposed as an adjunct in addiction treatment, including tobacco cigarette smoking. The physiological and biochemical mechanisms that could be affected by physical exercise in smokers and that ...
    • HPA-Axis Activity and Nutritional Status Correlation in Individuals with Alcohol Use Disorder 

      Georgakouli K., Manthou E., Fatouros I.G., Deli C.K., Koutedakis Y., Theodorakis Y., Jamurtas A.Z. (2022)
      Impaired activity of the hypothalamic–pituitary–adrenal axis (HPA-axis) is evident in alcohol use disorder (AUD), and may be implicated in various nutritional and metabolic alterations often seen in individuals with this ...
    • Links between HPA axis and adipokines: clinical implications in paradigms of stress-related disorders 

      Papargyri P., Zapanti E., Salakos N., Papargyris L., Bargiota A., Mastorakos G. (2018)
      Introduction: In the human organism, a constant interplay exists between the stress system [which includes the activity of the hypothalamic-pituitary-adrenal (HPA) axis] and the adipose tissue. This interplay is mediated ...
    • Role of exercise in the treatment of alcohol use disorders (review) 

      Manthou E., Georgakouli K., Fatouros I.G., Gianoulakis C., Theodorakis Y., Jamurtas A.Z. (2016)
      Excessive alcohol use can cause harmful effects on the human body, which are associated with serious health problems, and it can also lead to the development of alcohol use disorders (AUDs). There is certain evidence that ...
    • The role of hypothalamic inflammation in diet-induced obesity and its association with cognitive and mood disorders 

      Dionysopoulou S., Charmandari E., Bargiota A., Vlachos N., Mastorakos G., Valsamakis G. (2021)
      Obesity is often associated with cognitive and mood disorders. Recent evidence suggests that obesity may cause hypothalamic inflammation. Our aim was to investigate the hypothesis that there is a causal link between ...
    • Stress, female reproduction and pregnancy 

      Valsamakis G., Chrousos G., Mastorakos G. (2019)
      Stress is one of the commonest and underappreciated causes of reproductive frailty in women. The stress system leads to adaptive responses via mobilization of hormonal systems. Adaptability and resistance to stress are ...